Age Span Fellowship in Multiple Sclerosis and Related Neuroinflammatory Disorders

Overview

The Age Span Fellowship in Multiple Sclerosis and Related Neuroinflammatory Disorders offers Clinical and Clinical and Research tracks for adult neurology and pediatric neurology trainees. The mission of this program is to provide integrated, longitudinal care from childhood to adulthood and accepts BOTH pediatric and adult neurology applicants.

Training occurs with our distinguished faculty and supported by advanced practice providers, pharmacists, research coordinators, and social worker. The Multiple Sclerosis and Related Disorders Clinic at Penn is recognized as a National MS Comprehensive Care Center of Excellence, integrating ancillary services to provide comprehensive care and availability of basic science, translational, and clinical research studies. 

The Age Span Program seamlessly integrates education, patient care, and research with the Children's Hospital of Philadelphia (CHOP)

There are several opportunities to learn other neuroinflammatory conditions through the NMO and MOG-AD Disease Program, Undiagnosed White Matter Disorders Adult Neurogenetics Clinic, Neurosarcoidosis Clinic, and the Age-Span Women’s MS Program to develop well-rounded neuroinflammatory experts.

Fellowship curriculum

Clinical Track: 1-year training in diagnosis and management of Multiple Sclerosis and related disorders including NMOSD, MOGAD, granulomatous disease, and neurological manifestations of systemic disease. By the end of training fellows are expected to demonstrate comfort in management of these disorders and complete a scholarly project in their area of interest.

  • Funding: Past & Current
    • National MS Society 
    • Transverse Myelitis Association
    • Industry Supported
    • This track can support International Graduates with a J-1 Visa

Research and Clinical Track: This is a combined research and clinical training fellowship track that will be tailored to the individual fellow’s training and career goals.

  • Funding: Mentor-based funding (Includes T32 and UE5 Mechanisms).
  • Potential Mentors:
    • Dr. Amit Bar-Or
    • Dr. Jennifer Orthmann-Murphy
    • Dr. Matthew Schindler

Additional Training Opportunities:

  • Clinical Research Certificate Program
  • Master of Science in Clinical Epidemiology (MSCE) Degree program in the Center for Clinical Epidemiology and Biostatistics (CCEB).

Didactics

  • Fellows Bootcamp Lecture Series: Introduction to MS and related neuroinflammatory disorders evaluation and management.
  • Monthly journal club addressing both clinical and research topics.
  • Monthly Invited Speaker Seminar: Highlights national and international leaders, covering research (basic and clinical) and clinical care. 
  • Bi-monthly case conferences in collaboration with CHOP
  • ACTRIMS Didactic Lecture Series (ACTRIMS LMS - ACTRIMS Didactic Lecture Series (mclms.net))

Application process 

Requirement for applicants

  • Successful completion of an ACGME-accredited Neurology residency (or Canadian equivalent) prior to start of fellowship
  • Eligible for medical licensure in the state of Pennsylvania, including successful completion of USMLE Step 3 (or COMLEX Level 3)

July 2027 application cycle closed

Clinical Track (Adult and Pediatric Candidates): SF Match

July 2028 Application Cycle

  • Submit: cover letter, curriculum vitae, three letters of recommendation and a professional photo.
  • Application Registration Opens: Monday, November 2, 2026 : Applicants can register and begin uploading application materials.
  • Penn MS Fellowship Application Deadline: Friday January 8, 2027
    • Will not accept applications after this date.
  • Penn MS Fellowship Interviews: Early February to March 2027.
  • Rank Order List Deadline: Wednesday, April 28, 2027 @ 12:00 PM PT
  • Match Results Released: Wednesday, May 5, 2027 @ 9:00 AM PT

Research and Clinical Track (Adult and Pediatric Candidates): Not a Match

  • Submission Email: Please email the MSFellowshipDirectors@pennmedicine.upenn.edu to determine if post-doctoral training funding is available starting July 2027 and please include a proposed mentor.
  • Offers: Pending Mentor Funding.

Contact information

Juliana Adedipe
Email:
Juliana.Adedipe@pennmedicine.upenn.edu

Faculty

Headshot of Jennifer Orthmann-Murphy, MD, PhD Jennifer Orthmann-Murphy, MD, PhD
Co-Director, Multiple Sclerosis and Related Disorders Fellowship
Assistant Professor of Neurology
Visit Orthmann-Murphy Lab

Headshot of Rohini D. Samudralwar, MD Rohini D. Samudralwar, MD
Co-Director, Multiple Sclerosis and Related Disorders Fellowship
Associate Director of the Residency

Sarah Hopkins headshotSarah Hopkins, MD, MSPH
Co-Director, Multiple Sclerosis and Related Disorders Fellowship

Amit Bar-or headshotAmit Bar-Or, MD, FRCPC
Director, Center for Neuroinflammation and Neurotherapeutics
Chief, Multiple Sclerosis Division
Melissa and Paul Anderson President's Distinguished Professor

Headshot of Rachel Brandstadter, MDRachel Brandstadter, MD
Associate Professor of Neurology

Headshot of Dina Jacobs, MD Dina Jacob, MD
Clinical Director, Multiple Sclerosis and Related Disorders Center
Professor of Neurology

Clyde Markowitz, MD
Director, Multiple Sclerosis Center at Penn
Associate Professor of Neurology

Headshot of Laura Naydovich, MD Laura Naydovich, MD
Assistant Professor

Headshot of Christopher Perrone, MD Christopher Perrone, MD
Associate Professor of Clinical Neurology
Associate Clerkship Director

Headshot of Matthew Schindler, MD, PhD Matthew Schindler, MD, PhD
Assistant Professor of Neurology at the Pennsylvania Hospital