Our research faculty lead a broad range of programs funded by the National Institutes of Health, foundations, and corporate sponsors with in the rich of environment of the Perelman School of Medicine. These programs leverage Penn's many institutes and centers, including the Penn Cardiovascular Institute, the Institute for Translational Medicine and Therapeutics, the Institute for Diabetes, Obesity and Metabolism, the Leonard Davis Institute for Health Economics, and the Center for Clinical Epidemiology and Biostatistics. Please see below for more detail.
Arany lab
The Arany lab pursues a mechanistic understanding of metabolism in the cardiovascular system, and its impact on diabetes, heart failure, and other metabolic diseases. The lab incorporates a wide range of approaches, from basic molecular biology to human genetics and whole-organism metabolism.
- Zoltan Pierre Arany, MD, PhD
Associate Professor of Medicine and Cell and Developmental Biology
Director, Cardiovascular Metabolism Program (CVI)
zarany@pennmedicine.upenn.edu
Learn more about the Arany Lab
Cappola lab
The Cappola Lab focuses on heart failure mechanisms, genomics, and therapeutics with an emphasis on studies in human subjects
- Thomas P. Cappola, MD, ScM
William Smilow Professor
Chief, Division of Cardiovascular Medicine
Thomas.Cappola@pennmedicine.upenn.edu
Day lab
The Day Lab focuses on genetic heart muscle diseases. The research program integrates translational and clinical science, with a primary focus on hypertrophic cardiomyopathy. Understanding the full spectrum of disease evolution and progression, from the primary effects of sarcomere gene mutations in cardiac muscle cells to the phenotypic expression and predictors of adverse outcomes in patients.
- Sharlene Day, MD
Director, Translational Research
Division of Cardiovascular Medicine and Cardiovascular Institute
Professor of Medicine
Sharlene.Day@pennmedicine.upenn.edu
Epstein lab
The Epstein Lab focuses on stem cell and developmental biology with an emphasis on epigenetics and nuclear architecture.
- Jonathan A. Epstein, MD
Executive Vice Dean and Chief Scientific Officer
William Wikoff Smith Professor of Medicine
epsteinj@pennmedicine.upenn.edu
Kahn lab
The Kahn Lab investigates many aspects of vascular and cardiovascular biology, including blood and lymphatic vascular development and disease, and the role of fluid forces in cardiovascular biology, and hemostasis.
- Mark Kahn, MD
Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor
Director, Center for Vascular Biology (CVI)
markkahn@pennmedicine.upenn.edu
Kelly lab
The Kelly Lab is interested in the control of energy metabolism and mitochondrial function in the developing and diseased heart.
- Daniel Kelly, MD
Director, Penn Cardiovascular Institute (CVI)
Willard and Rhoda Ware Professor of Medicine
dankelly@pennmedicine.upenn.edu
Learn more about the Kelly Lab
Ky lab
The Ky Lab is interested in understanding the biologic and functional cardiovascular effects of cancer therapies in humans.
- Bonnie Ky, MD, MSCE
Scientific Director, Cardio-Oncology Program
Founders Professor of Cardio-Oncology
Director, Penn Center for Quantitative Echocardiography
Director, Thalheimer Center for Cardio-Oncology
Bonnie.Ky@pennmedicine.upenn.edu
Margulies lab
The Margulies Lab examines mechanisms of myocardial structural and functional remodeling to identify targets for therapeutic interventions.
- Kenneth B. Margulies, MD
Professor of Medicine and Physiology
Director, Cardiovascular Clinical Research Unit
Director, Heart Failure and Transplant Research and Training
Kenneth.Margulies@pennmedicine.upenn.edu
Learn more about the Margulies Lab
Morrisey lab
The goal of the Morrisey Lab is to define the molecular mechanisms underlying lung and cardiac development and tissue regeneration using a multi-platform approach including animal and human model systems.
- Edward Morrisey, PhD
Professor of Cell and Developmental Biology
Director, Penn Center for Pulmonary Biology
The Robinette Foundation Professor of Cardiovascular Medicine
Scientific Director, Penn Institute for Regenerative Medicine
emorrise@pennmedicine.upenn.edu
Learn more about the Morrisey Lab
Musunuru lab
The Musunuru Lab focuses on the genetics of cardiovascular and metabolic diseases and seeks to identify naturally occurring genetic variants that predispose to or protect against disease and can be used to develop therapies to protect the entire population.
- Kiran Musunuru, MD, PhD, MPH
Professor of Cardiovascular Medicine and Genetics
Director, Genetic and Epigenetic Origins of Disease Program (CVI)
Scientific Director, Center for Inherited Cardiovascular Disease
kmus@pennmedicine.upenn.edu
Scherrer-Crosbie lab
The Scherrer-Crosbie Lab is interested in better understanding and detecting subclinical myocardial disease in cancer and in metabolic and adipose dysfunction.
- Marielle Scherrer-Crosbie, MD, PhD
Director, Cardiac Ultrasound Laboratory
Professor of Medicine at the Hospital of the University of Pennsylvania
Marielle.Scherrer-Crosbie@uphs.upenn.edu